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Altered Subcellular Distribution of c-Abl in Alzheimer's Disease

c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-β-induced toxicity and tau phosphorylation. To further characterize a potential role of c-Abl in...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jing, Zheng, Caltagarone, John, Bowser, Robert
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829466/
https://ncbi.nlm.nih.gov/pubmed/19363261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-1062
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