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PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease

Mitochondrial anomalies have been previously reported in patients′ brain and peripheral tissue, suggesting their relevance in sporadic Alzheimer's disease (AD). The present work evaluates mitochondrial function and recycling in human fibroblasts and brain biopsies. Functional studies using pati...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Martín-Maestro, Patricia, Gargini, Ricardo, Perry, George, Avila, Jesús, García-Escudero, Vega
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743695/
https://ncbi.nlm.nih.gov/pubmed/26721933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv616
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