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PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease

Mitochondrial anomalies have been previously reported in patients′ brain and peripheral tissue, suggesting their relevance in sporadic Alzheimer's disease (AD). The present work evaluates mitochondrial function and recycling in human fibroblasts and brain biopsies. Functional studies using pati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Mol Genet
Egile Nagusiak: Martín-Maestro, Patricia, Gargini, Ricardo, Perry, George, Avila, Jesús, García-Escudero, Vega
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743695/
https://ncbi.nlm.nih.gov/pubmed/26721933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv616
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