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PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease
Mitochondrial anomalies have been previously reported in patients′ brain and peripheral tissue, suggesting their relevance in sporadic Alzheimer's disease (AD). The present work evaluates mitochondrial function and recycling in human fibroblasts and brain biopsies. Functional studies using pati...
Gespeichert in:
| Veröffentlicht in: | Hum Mol Genet |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743695/ https://ncbi.nlm.nih.gov/pubmed/26721933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv616 |
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