In Vivo Stable Transduction of Humanized Liver Tissue in Chimeric Mice via High-Capacity Adenovirus–Lentivirus Hybrid Vector

We developed hybrid vectors employing high-capacity adenovirus as a first-stage carrier encoding all the components required for in situ production of a second-stage lentivirus, thereby achieving stable transgene expression in secondary target cells. Such vectors have never previously been tested in...

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Autors principals: Kubo, Shuji, Kataoka, Miho, Tateno, Chise, Yoshizato, Katsutoshi, Kawasaki, Yoshiko, Kimura, Takahiro, Faure-Kumar, Emmanuelle, Palmer, Donna J., Ng, Philip, Okamura, Haruki, Kasahara, Noriyuki
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829460/
https://ncbi.nlm.nih.gov/pubmed/19725756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.027
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