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Fifteen Years of Gene Therapy Based on Chimeric Antigen Receptors: “Are We Nearly There Yet?”

“T-body” or chimeric antigen receptor (CAR) technology, which combines the specificity of an antibody with the homing, tissue penetration, and target cell destruction of T cells, was first described in 1993. After many years of unmet promise, significant improvements in gene transfer, including the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Dotti, Gianpietro, Savoldo, Barbara, Brenner, Malcolm
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829458/
https://ncbi.nlm.nih.gov/pubmed/19702437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.142
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