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Fifteen Years of Gene Therapy Based on Chimeric Antigen Receptors: “Are We Nearly There Yet?”
“T-body” or chimeric antigen receptor (CAR) technology, which combines the specificity of an antibody with the homing, tissue penetration, and target cell destruction of T cells, was first described in 1993. After many years of unmet promise, significant improvements in gene transfer, including the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Mary Ann Liebert, Inc.
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829458/ https://ncbi.nlm.nih.gov/pubmed/19702437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.142 |
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