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(13)C Isotope Effect On the Reaction Catalyzed by Prephenate Dehydratase

The (13)C isotope effect for the conversion of prephenate to phenylpyruvate by the enzyme prephenate dehydratase from Methanocaldococcus jannaschii is 1.0334 ± 0.0006. The size of this isotope effect suggests that the reaction is concerted. From the X-ray structure of a related enzyme, it appears th...

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Detalhes bibliográficos
Main Authors: Van Vleet, Jeremy, Kleeb, Andreas, Kast, Peter, Hilvert, Donald, Cleland, W. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829336/
https://ncbi.nlm.nih.gov/pubmed/19948253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.11.018
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