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Plasmid-Encoded Interleukin-15 Receptor α Enhances Specific Immune Responses Induced by a DNA Vaccine In Vivo

Plasmid-encoded DNA vaccines appear to be a safe and effective method for delivering antigen; however, the immunogenicity of such vaccines is often suboptimal. Cytokine adjuvants including interleukin (IL)-12, RANTES, granulocyte-macrophage colony-stimulating factor, IL-15, and others have been used...

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Autori principali: Kraynyak, Kimberly A., Kutzler, Michele A., Cisper, Neil J., Laddy, Dominick J., Morrow, Matthew P., Waldmann, Thomas A., Weiner, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829284/
https://ncbi.nlm.nih.gov/pubmed/19530914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.025
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