High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model

Interleukin (IL)-15, is a cytokine that is important for the maintenance of long-lasting, high-avidity T cell response to invading pathogens and has, therefore, been used in vaccine and therapeutic platforms as an adjuvant. In addition to pure protein delivery, plasmids encoding the IL-15 gene have...

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Main Authors: Yin, Jiangmei, Dai, Anlan, Laddy, Dominick J., Yan, Jian, Arango, Tatiana, Khan, Amir S., Lewis, Mark G., Andersen, Hanne, Kutzler, Michele A., Draghia-Akli, Ruxandra, Weiner, David B., Boyer, Jean D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118595/
https://ncbi.nlm.nih.gov/pubmed/19683780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.07.017
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