Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens

BACKGROUND: The persistent evolution of highly pathogenic avian influenza (HPAI) highlights the need for novel vaccination techniques that can quickly and effectively respond to emerging viral threats. We evaluated the use of optimized consensus influenza antigens to provide broad protection against...

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Detalhes bibliográficos
Main Authors: Laddy, Dominick J., Yan, Jian, Kutzler, Michele, Kobasa, Darwyn, Kobinger, Gary P., Khan, Amir S., Greenhouse, Jack, Sardesai, Niranjan Y., Draghia-Akli, Ruxandra, Weiner, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429965/
https://ncbi.nlm.nih.gov/pubmed/18575608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002517
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