Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens

BACKGROUND: The persistent evolution of highly pathogenic avian influenza (HPAI) highlights the need for novel vaccination techniques that can quickly and effectively respond to emerging viral threats. We evaluated the use of optimized consensus influenza antigens to provide broad protection against...

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Autori principali: Laddy, Dominick J., Yan, Jian, Kutzler, Michele, Kobasa, Darwyn, Kobinger, Gary P., Khan, Amir S., Greenhouse, Jack, Sardesai, Niranjan Y., Draghia-Akli, Ruxandra, Weiner, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429965/
https://ncbi.nlm.nih.gov/pubmed/18575608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002517
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