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Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A(1) receptor ligands

BACKGROUND AND PURPOSE: The introduction of fluorescence-based techniques, and in particular the development of fluorescent ligands, has allowed the study of G protein-coupled receptor pharmacology at the single cell and single molecule level. This study evaluated how the physicochemical nature of t...

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Autori principali: Baker, Jillian G, Middleton, Richard, Adams, Luke, May, Lauren T, Briddon, Stephen J, Kellam, Barrie, Hill, Stephen J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829203/
https://ncbi.nlm.nih.gov/pubmed/20105183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00488.x
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