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A fast dynamic mode of the EF-G-bound ribosome
A key intermediate in translocation is an ‘unlocked state' of the pre-translocation ribosome in which the P-site tRNA adopts the P/E hybrid state, the L1 stalk domain closes and ribosomal subunits adopt a ratcheted configuration. Here, through two- and three-colour smFRET imaging from multiple...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829159/ https://ncbi.nlm.nih.gov/pubmed/20033061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.384 |
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