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Spontaneous formation of the unlocked state of the ribosome is a multistep process

The mechanism of substrate translocation through the ribosome is central to the rapid and faithful translation of mRNA into proteins. The rate-limiting step in translocation is an unlocking process that includes the formation of an “unlocked” intermediate state, which requires the convergence of lar...

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Hlavní autoři: Munro, James B., Altman, Roger B., Tung, Chang-Shung, Cate, Jamie H. D., Sanbonmatsu, Kevin Y., Blanchard, Scott C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818936/
https://ncbi.nlm.nih.gov/pubmed/20018653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908597107
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