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A fast dynamic mode of the EF-G-bound ribosome

A key intermediate in translocation is an ‘unlocked state' of the pre-translocation ribosome in which the P-site tRNA adopts the P/E hybrid state, the L1 stalk domain closes and ribosomal subunits adopt a ratcheted configuration. Here, through two- and three-colour smFRET imaging from multiple...

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Main Authors: Munro, James B, Altman, Roger B, Tung, Chang-Shung, Sanbonmatsu, Kevin Y, Blanchard, Scott C
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829159/
https://ncbi.nlm.nih.gov/pubmed/20033061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.384
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