Co-Expression of DevR and DevR(N)-Aph Proteins Is Associated with Hypoxic Adaptation Defect and Virulence Attenuation of Mycobacterium tuberculosis

BACKGROUND: The DevR response regulator is implicated in both hypoxic adaptation and virulence of Mycobacterium tuberculosis (M. tb). DevR regulon genes are powerfully induced in vivo implicating them in bacterial adaptation to host control strategies. A better understanding of DevR function will il...

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Hauptverfasser: Majumdar, Shyamasree De, Sharma, Deepak, Vashist, Atul, Kaur, Kohinoor, Taneja, Neetu Kumra, Chauhan, Santosh, Challu, Vijay K., Ramanathan, V. D., Balasangameshwara, V., Kumar, Prahlad, Tyagi, Jaya Sivaswami
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829086/
https://ncbi.nlm.nih.gov/pubmed/20195478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009448
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