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Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

VEGF can be secreted in multiple isoforms with variable affinity for extracellular proteins and different abilities to induce vascular morphogenesis, but the molecular mechanisms behind these effects remain unclear. Here, we show molecular distinctions between signaling initiated from soluble versus...

詳細記述

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書誌詳細
主要な著者: Chen, Tom T., Luque, Alfonso, Lee, Sunyoung, Anderson, Sean M., Segura, Tatiana, Iruela-Arispe, M. Luisa
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828913/
https://ncbi.nlm.nih.gov/pubmed/20176926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906044
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