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Nitric oxide induces airway smooth muscle cell relaxation by decreasing the frequency of agonist-induced Ca(2+) oscillations

Nitric oxide (NO) induces airway smooth muscle cell (SMC) relaxation, but the underlying mechanism is not well understood. Consequently, we investigated the effects of NO on airway SMC contraction, Ca(2+) signaling, and Ca(2+) sensitivity in mouse lung slices with phase-contrast and confocal microsc...

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Hlavní autoři: Perez-Zoghbi, Jose F., Bai, Yan, Sanderson, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828908/
https://ncbi.nlm.nih.gov/pubmed/20176853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910365
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