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Airway smooth muscle relaxation results from a reduction in the frequency of Ca(2+ )oscillations induced by a cAMP-mediated inhibition of the IP(3 )receptor

BACKGROUND: It has been shown that the contractile state of airway smooth muscle cells (SMCs) in response to agonists is determined by the frequency of Ca(2+ )oscillations occurring within the SMCs. Therefore, we hypothesized that the relaxation of airway SMCs induced by agents that increase cAMP re...

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Autori principali: Bai, Yan, Sanderson, Michael J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459146/
https://ncbi.nlm.nih.gov/pubmed/16504084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-34
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