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Studies of RNA/DNA Polypurine Tracts

During reverse transcription, an RNA polypurine tract (PPT) resists digestion by reverse transcriptase (RT) and primes plus-strand DNA synthesis. In this issue of Chemistry & Biology, Yi-Brunozzi et al. [1] report structural studies of PPTs, illuminating how they are recognized by RT.

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Detalhes bibliográficos
Main Authors: Fitzgerald, Megan E., Drohat, Alexander C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828867/
https://ncbi.nlm.nih.gov/pubmed/18355716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.03.001
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