Coordinating the Initial Steps of Base Excision Repair: APURINIC/APYRIMIDINIC ENDONUCLEASE 1 ACTIVELY STIMULATES THYMINE DNA GLYCOSYLASE BY DISRUPTING THE PRODUCT COMPLEX

DNA glycosylases initiate base excision repair by removing damaged or mismatched bases, producing apurinic/apyrimidinic (AP) DNA. For many glycosylases, the AP-DNA remains tightly bound, impeding enzymatic turnover. A prominent example is thymine DNA glycosylase (TDG), which removes T from G·T mispa...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Fitzgerald, Megan E., Drohat, Alexander C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2008
Aiheet:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583297/
https://ncbi.nlm.nih.gov/pubmed/18805789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805504200
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia