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RacGTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP
Elevation in intracellular cAMP level has been associated with increased endothelial barrier integrity and linked to the activation of protein kinase A (PKA). Recent studies have shown a novel mechanism of cAMP-mediated endothelial barrier regulation via cAMP-dependent nucleotide exchange factor Epa...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828820/ https://ncbi.nlm.nih.gov/pubmed/19962392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2009.11.007 |
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