Carregant...

Asymmetric Synthesis of the Core of AMPTD, the Key Amino Acid of Microsclerodermins F-I

We report a stereoselective synthesis of the five consecutive stereocenters of AMPTD in seven steps. Highlights include an Evans glycolate aldol reaction, the use of a Weinreb amide as an aldehyde masking group, and a Mannich reaction with an Ellman-type chiral sulfimine.

Guardat en:
Dades bibliogràfiques
Autors principals: Burnett, Cameron M., Williams, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828631/
https://ncbi.nlm.nih.gov/pubmed/20191096
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!