Increased α-Defensins 1-3 Production by Dendritic Cells in HIV-Infected Individuals Is Associated with Slower Disease Progression

BACKGROUND: Defensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce α-defensins1-3 and that α-defensins1-3 modulate DC generation and maturation. Since DC-HIV interaction...

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Main Authors: Rodríguez-García, Marta, Climent, Núria, Oliva, Harold, Casanova, Víctor, Franco, Rafael, Leon, Agathe, Gatell, José M., García, Felipe, Gallart, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828484/
https://ncbi.nlm.nih.gov/pubmed/20195543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009436
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