Dendritic Cells Exposed to MVA-Based HIV-1 Vaccine Induce Highly Functional HIV-1-Specific CD8(+) T Cell Responses in HIV-1-Infected Individuals

Currently, MVA virus vectors carrying HIV-1 genes are being developed as HIV-1/AIDS prophylactic/therapeutic vaccines. Nevertheless, little is known about the impact of these vectors on human dendritic cells (DC) and their capacity to present HIV-1 antigens to human HIV-specific T cells. This study...

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Main Authors: Climent, Núria, Guerra, Susana, García, Felipe, Rovira, Cristina, Miralles, Laia, Gómez, Carmen Elena, Piqué, Núria, Gil, Cristina, Gatell, José María, Esteban, Mariano, Gallart, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097254/
https://ncbi.nlm.nih.gov/pubmed/21625608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019644
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