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EVIDENCE FOR ALTERED ACTIVITY OF THE IL-6 PATHWAY IN CHRONIC RHINOSINUSITIS WITH NASAL POLYPS

BACKGROUND: Interleukin 6 (IL-6) activates Th17 cells and regulates the response of B-lymphocytes and T regulatory cells. The IL-6 receptor and the membrane protein, gp130, form an active signaling complex that signals through STAT3 and other signaling molecules. Both the IL-6 receptor (IL-6R) and g...

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Библиографические подробности
Главные авторы: Peters, Anju T., Kato, Atsushi, Zhang, Ning, Conley, David B., Suh, Lydia, Tancowny, Brian, Carter, Derek, Carr, Tara, Radtke, Michael, Hulse, Kathryn E., Seshadri, Sudarshan, Chandra, Rakesh, Grammer, Leslie C., Harris, Kathleen E., Kern, Robert, Schleimer, Robert P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828355/
https://ncbi.nlm.nih.gov/pubmed/20159251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.10.072
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