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GTPase-Rac enhances depolarization-induced superoxide production by the macula densa during tubuloglomerular feedback
Superoxide (O(2)(−) ) enhances tubuloglomerular feedback (TGF) by scavenging nitric oxide at the macula densa (MD). The primary source of O(2)(−) in the MD during TGF is NADPH oxidase, which is activated by membrane depolarization. While Rac, a small GTP-binding protein, has been shown to enhance NA...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Physiological Society
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828178/ https://ncbi.nlm.nih.gov/pubmed/20007513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00622.2009 |
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