Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues

Pentameric ligand-gated ion channels (pLGICs) are widely expressed in the animal kingdom and are key players of neurotransmission by acetylcholine (ACh), γ-amminobutyric acid (GABA), glycine and serotonin. It is now established that this family has a prokaryotic origin, since more than 20 homologues...

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Autores principales: Corringer, Pierre-Jean, Baaden, Marc, Bocquet, Nicolas, Delarue, Marc, Dufresne, Virginie, Nury, Hugues, Prevost, Marie, Van Renterghem, Catherine
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2010
Materias:
Symposium Section Reviews: Cys-Loop Ligand-Gated Ion Channels and Receptors
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828131/
https://ncbi.nlm.nih.gov/pubmed/19995852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.183160
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