Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS

Motivation: Epistasis, the presence of gene–gene interactions, has been hypothesized to be at the root of many common human diseases, but current genome-wide association studies largely ignore its role. Multifactor dimensionality reduction (MDR) is a powerful model-free method for detecting epistati...

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Detaylı Bibliyografya
Asıl Yazarlar: Greene, Casey S., Sinnott-Armstrong, Nicholas A., Himmelstein, Daniel S., Park, Paul J., Moore, Jason H., Harris, Brent T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2010
Konular:
Applications Note
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828117/
https://ncbi.nlm.nih.gov/pubmed/20081222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq009
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