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Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K(+) channels

BACKGROUND AND PURPOSE: ATP-sensitive potassium channels (K(ATP) channels) in beta cells are a major target for insulinotropic drugs. Here, we studied the effects of selected stimulatory and inhibitory pharmacological agents in islets lacking K(ATP) channels. EXPERIMENTAL APPROACH: We compared insul...

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Detalhes bibliográficos
Main Authors: Szollosi, A, Nenquin, M, Henquin, JC
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828030/
https://ncbi.nlm.nih.gov/pubmed/20128805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00588.x
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