Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis

Tropomyosin-related kinase receptor C (TrkC) is a neurotrophin receptor with tyrosine kinase activity that was expected to be oncogenic. However, it has several characteristics of a tumor suppressor: its expression in tumors has often been associated with good prognosis; and it was recently demonstr...

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Main Authors: Bouzas-Rodriguez, Jimena, Cabrera, Jorge Ruben, Delloye-Bourgeois, Céline, Ichim, Gabriel, Delcros, Jean-Guy, Raquin, Marie-Anne, Rousseau, Raphaël, Combaret, Valérie, Bénard, Jean, Tauszig-Delamasure, Servane, Mehlen, Patrick
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2010
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827960/
https://ncbi.nlm.nih.gov/pubmed/20160348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41013
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