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The TrkC receptor induces apoptosis when the dependence receptor notion meets the neurotrophin paradigm

The TrkC/NT-3 receptor/ligand pair is believed to be part of the classic neurotrophic theory claiming that neuronal death occurs by default when neurotrophic factors become limited, through loss of survival signals. Here, we show that TrkC is a dependence receptor and, as such, induces caspase-depen...

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Detalhes bibliográficos
Main Authors: Tauszig-Delamasure, Servane, Yu, Li-Ying, Cabrera, Jorge Ruben, Bouzas-Rodriguez, Jimena, Mermet-Bouvier, Catherine, Guix, Catherine, Bordeaux, Marie-Claire, Arumäe, Urmas, Mehlen, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948910/
https://ncbi.nlm.nih.gov/pubmed/17686986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701243104
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