Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

A paucity of versatile small animal models of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection has been an impediment to both furthering understanding of virus biology and testing antiviral therapies. We recently described a regulatable system for repopulating the liver of immunodeficie...

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Bibliographic Details
Main Authors: Bissig, Karl-Dimiter, Wieland, Stefan F., Tran, Phu, Isogawa, Masanori, Le, Tam T., Chisari, Francis V., Verma, Inder M.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2010
Subjects:
Technical Advance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827952/
https://ncbi.nlm.nih.gov/pubmed/20179355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40094
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