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Repopulation of adult and neonatal mice with human hepatocytes: A chimeric animal model
We report the successful transplantation of human hepatocytes in immunodeficient, fumarylacetoacetate hydrolase-deficient (fah(−/−)) mice. Engraftment occurs over the entire liver acinus upon transplantation. A few weeks after transplantation, increasing concentrations of human proteins (e.g., human...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2154461/ https://ncbi.nlm.nih.gov/pubmed/18077355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710528105 |
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