Critical Role of Tissue Kallikrein in Vessel Formation and Maturation: Implications for Therapeutic Revascularization

OBJECTIVE: Human Tissue Kallikrein (hKLK1) overexpression promotes an enduring neovascularization of ischemic tissue, yet the cellular mechanisms of hKLK1-induced arteriogenesis remain unknown. Furthermore, no previous study has compared the angiogenic potency of hKLK1, with its loss of function pol...

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Hauptverfasser: Stone, Oliver A., Richer, Christine, Emanueli, Costanza, van Weel, Vincent, Quax, Paul H.A., Katare, Rajesh, Kraenkel, Nicolle, Campagnolo, Paola, Barcelos, Luciola S., Siragusa, Mauro, Sala-Newby, Graciela B., Baldessari, Danila, Mione, Marina, Vincent, Marie P., Benest, Andrew V., Zen, Ayman Al Haj, Gonzalez, Julien, Bates, David O., Alhenc-Gelas, Francois, Madeddu, Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827862/
https://ncbi.nlm.nih.gov/pubmed/19164804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.182139
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