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Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis
Hypoxic response and inflammation both involve the action of the hypoxia-inducible transcription factors HIF-1α and HIF-2α. Previous studies have revealed that both HIF-α proteins are in a number of aspects similarly regulated post-translationally. However, the functional interrelationship of these...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827844/ https://ncbi.nlm.nih.gov/pubmed/20194441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1881410 |
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