The Chemokine MIP1α/CCL3 Determines Pathology in Primary RSV Infection by Regulating the Balance of T Cell Populations in the Murine Lung

BACKGROUND: CD8 T cells assist in the clearance of respiratory syncytial virus (RSV) infection from the lungs. However, disease after RSV infection is in part caused by excessive T cell activity, and a balance is therefore needed between beneficial and harmful cellular immune responses. The chemokin...

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Autori principali: Tregoning, John S., Pribul, Philippa K., Pennycook, Alasdair M. J., Hussell, Tracy, Wang, Belinda, Lukacs, Nicholas, Schwarze, Jurgen, Culley, Fiona J., Openshaw, Peter J. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827540/
https://ncbi.nlm.nih.gov/pubmed/20195359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009381
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