Alveolar Macrophages Are a Major Determinant of Early Responses to Viral Lung Infection but Do Not Influence Subsequent Disease Development

Macrophages are abundant in the lower respiratory tract. They play a central role in the innate response to infection but may also modulate excessive inflammation. Both macrophages and ciliated epithelial cells respond to infection by releasing soluble mediators, leading to the recruitment of innate...

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Detalhes bibliográficos
Main Authors: Pribul, Philippa K., Harker, James, Wang, Belinda, Wang, Hongwei, Tregoning, John S., Schwarze, Jürgen, Openshaw, Peter J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293049/
https://ncbi.nlm.nih.gov/pubmed/18287232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02541-07
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