Alveolar Macrophages Are a Major Determinant of Early Responses to Viral Lung Infection but Do Not Influence Subsequent Disease Development

Macrophages are abundant in the lower respiratory tract. They play a central role in the innate response to infection but may also modulate excessive inflammation. Both macrophages and ciliated epithelial cells respond to infection by releasing soluble mediators, leading to the recruitment of innate...

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Bibliographische Detailangaben
Hauptverfasser: Pribul, Philippa K., Harker, James, Wang, Belinda, Wang, Hongwei, Tregoning, John S., Schwarze, Jürgen, Openshaw, Peter J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293049/
https://ncbi.nlm.nih.gov/pubmed/18287232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02541-07
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