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Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes

The crystal structure of the unbound form of HIV-1 subtype A protease (PR) has been determined to 1.7 Å resolution and refined as a homodimer in the hexagonal space group P6(1) to an R (cryst) of 20.5%. The structure is similar in overall shape and fold to the previously determined subtype B, C and...

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Autori principali: Robbins, Arthur H., Coman, Roxana M., Bracho-Sanchez, Edith, Fernandez, Marty A., Gilliland, C. Taylor, Li, Mi, Agbandje-McKenna, Mavis, Wlodawer, Alexander, Dunn, Ben M., McKenna, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827345/
https://ncbi.nlm.nih.gov/pubmed/20179334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909054298
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