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Expression, purification and preliminary X-ray crystallographic studies of the human immunodeficiency virus 1 subtype C protease

Crystals of the human immunodeficiency virus 1 (HIV-1) subtype C protease (PR) complexed with the clinically used inhibitors indinavir (IDV) and nelfinavir (NFV) have been grown in the monoclinic space group P2(1), with mean unit-cell parameters a = 46.7 (±0.1), b = 59.8 (±0.3), c = 87.0 (±0.4) Å, β...

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Detalhes bibliográficos
Main Authors: Coman, Roxana M., Robbins, Arthur, Goodenow, Maureen M., McKenna, Robert, Dunn, Ben M.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330223/
https://ncbi.nlm.nih.gov/pubmed/17401206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910701161X
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