Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9

Adeno-associated virus (AAV) serotype 9, which is under development for gene-delivery applications, shows significantly enhanced capsid-associated transduction efficiency in muscle compared with other AAV serotypes. With the aim of characterizing the structural determinants of this property, the pur...

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Autores principales: Mitchell, Matthew, Nam, Hyun-Joo, Carter, Adam, McCall, Angela, Rence, Chelsea, Bennett, Antonette, Gurda, Brittney, McKenna, Robert, Porter, Mark, Sakai, Yoshihisa, Byrne, Barry J., Muzyczka, Nicholas, Aslanidi, George, Zolotukhin, Sergei, Agbandje-McKenna, Mavis
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2009
Materias:
Crystallization Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705643/
https://ncbi.nlm.nih.gov/pubmed/19574648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109021460
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