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Affinity of antigen encounter and other early B-cell signals determine B-cell fate

Three possible effector fates await the naïve follicular B cell following antigen stimulation in thymus-dependent reactions. Short-lived plasma cells produce an initial burst of germline-encoded protective antibodies, and long-lived plasma cells and memory B cells arise from the germinal center and...

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Autors principals: Benson, Micah J, Erickson, Loren D, Gleeson, Michael W, Noelle, Randolph J
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827202/
https://ncbi.nlm.nih.gov/pubmed/17433651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2007.04.009
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