Recombinant tumor necrosis factor increases pulmonary vascular permeability independent of neutrophils.
We studied the effects of intravenous infusion of recombinant human tumor necrosis factor type alpha (rTNF-alpha; 12 micrograms/kg) on lung fluid balance in sheep prepared with chronic lung lymph fistulas. The role of neutrophils was examined in sheep made neutropenic with hydroxyurea (200 mg/kg for...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282710/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3143114/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9219 |
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