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The K65R mutation in HIV-1 reverse transcriptase: genetic barriers, resistance profile and clinical implications
Resistance to antiviral therapy is the limiting factor in the successful management of HIV. In general, the K65R mutation is rarely selected (1.7–4%) with tenofovir disoproxil fumarate (TDF), abacavir (ABC), didanosine (ddI), and stavudine (d4T), as compared with the high incidence (>40%) of thym...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826981/ https://ncbi.nlm.nih.gov/pubmed/20190870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/hiv.09.40 |
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