Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

Chromosomes can be specifically stained in metaphase spreads and interphase nuclei by in situ hybridization with entire chromosome-specific DNA libraries. Unlabeled human genomic DNA is used to inhibit the hybridization of sequences in the library that bind to multiple chromosomes. The target chromo...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Pinkel, D, Landegent, J, Collins, C, Fuscoe, J, Segraves, R, Lucas, J, Gray, J
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1988
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282679/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2973607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9138
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