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Synergistic effect of cAMP and palmitate in promoting altered mitochondrial function and cell death in HepG2 cells

Saturated free fatty acids (FFAs), e.g. palmitate, have long been shown to induce toxicity and cell death in various types of cells. In this study, we demonstrate that cAMP synergistically amplifies the effect of palmitate on the induction of cell death in human hepatocellular carcinoma cell line, H...

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Hlavní autoři: Zhang, Linxia, Seitz, Linsey C., Abramczyk, Amy M., Chan, Christina
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826503/
https://ncbi.nlm.nih.gov/pubmed/20026039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.12.008
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