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Experimental and Computational Studies Investigating Trehalose Protection of HepG2 Cells from Palmitate-Induced Toxicity

Understanding the mechanism of saturated fatty acid-induced hepatocyte toxicity may provide insight into cures for diseases such as obesity-associated cirrhosis. Trehalose, a nonreducing disaccharide shown to protect proteins and cellular membranes from inactivation or denaturation caused by differe...

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Bibliografiske detaljer
Main Authors: Leekumjorn, Sukit, Wu, Yifei, Sum, Amadeu K., Chan, Christina
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267146/
https://ncbi.nlm.nih.gov/pubmed/18096630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.120717
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