Rac1 and Cdc42 are regulators of HRas(V12)-transformation and angiogenic factors in human fibroblasts

BACKGROUND: The activities of Rac1 and Cdc42 are essential for HRas-induced transformation of rodent fibroblasts. What is more, expression of constitutively activated mutants of Rac1 and/or Cdc42 is sufficient for their malignant transformation. The role for these two Rho GTPases in HRas-mediated tr...

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Detaylı Bibliyografya
Asıl Yazarlar: Appledorn, Daniel M, Dao, Kim-Hien T, O'Reilly, Sandra, Maher, Veronica M, McCormick, J Justin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826294/
https://ncbi.nlm.nih.gov/pubmed/20067638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-13
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