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Rac1 and Cdc42 are regulators of HRas(V12)-transformation and angiogenic factors in human fibroblasts
BACKGROUND: The activities of Rac1 and Cdc42 are essential for HRas-induced transformation of rodent fibroblasts. What is more, expression of constitutively activated mutants of Rac1 and/or Cdc42 is sufficient for their malignant transformation. The role for these two Rho GTPases in HRas-mediated tr...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826294/ https://ncbi.nlm.nih.gov/pubmed/20067638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-13 |
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