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Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences
Expected and observed effects of volume exclusion on the free energy of rigid and flexible macromolecules in crowded and confined systems, and consequent effects of crowding and confinement on macromolecular reaction rates and equilibria are summarized. Findings from relevant theoretical/simulation...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2008
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826134/ https://ncbi.nlm.nih.gov/pubmed/18573087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biophys.37.032807.125817 |
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