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Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences

Expected and observed effects of volume exclusion on the free energy of rigid and flexible macromolecules in crowded and confined systems, and consequent effects of crowding and confinement on macromolecular reaction rates and equilibria are summarized. Findings from relevant theoretical/simulation...

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Détails bibliographiques
Auteurs principaux: Zhou, Huan-Xiang, Rivas, Germán, Minton, Allen P.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826134/
https://ncbi.nlm.nih.gov/pubmed/18573087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biophys.37.032807.125817
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