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Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences

Expected and observed effects of volume exclusion on the free energy of rigid and flexible macromolecules in crowded and confined systems, and consequent effects of crowding and confinement on macromolecular reaction rates and equilibria are summarized. Findings from relevant theoretical/simulation...

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Detalhes bibliográficos
Main Authors: Zhou, Huan-Xiang, Rivas, Germán, Minton, Allen P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826134/
https://ncbi.nlm.nih.gov/pubmed/18573087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biophys.37.032807.125817
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